Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Jul 14 - Jul 19
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
WWOX Recombinant Rabbit mAb (S-R298)Product Specification Host Rabbit Antigen WWOX Synonyms WW domain containing oxidoreductase, Fragile site FRA16D oxidoreductase, Short chain dehydrogenase reductase family 41C member 1, FOR, SDR41C1, WOX1 Location Cytoplasm, Nucleus Accession Q9NZC7 Clone Number S R298 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P, IP Reactivity Hu, Ms, Rt Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance
Product Specification
| Host | Rabbit |
| Antigen | WWOX |
| Synonyms | WW domain-containing oxidoreductase, Fragile site FRA16D oxidoreductase, Short chain dehydrogenase/reductase family 41C member 1, FOR, SDR41C1, WOX1 |
| Location | Cytoplasm, Nucleus |
| Accession | Q9NZC7 |
| Clone Number | S-R298 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P, IP |
| Reactivity | Hu, Ms, Rt |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05%BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | null |
| IP | 1:50 | null |
| IHC-P | 1:100 | null |
Background
WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. The highest normal expression of WWOX is detected in hormonally regulated tissues such as testis, ovary, and prostate. This expression pattern and the presence of an SRD domain suggest a role for this protein in steroid metabolism. WWOX is more than 90% identical to the mouse protein, which is an essential mediator of tumor necrosis factor-alpha-induced apoptosis, suggesting a similar, important role in apoptosis for the human protein. In addition, there is evidence that this protein behaves as a suppressor of tumor growth.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy
4.2 ★★★★★
Based on 909 reviews
Sort
Product Reviews
★★★★★ 4
Favorite chew toy
Size: Medium, Style: Bristle Bone
Pros: this is our dog’s favorite toy. She loves to eat but isn’t much for chewing. At 2 years old, her teeth were already looking pretty bad because she swallows everything whole. That makes most chew toys dangerous. This is the first toy that she chews aggressively. At first we had to give it to her in short spurts because her gums bled. That’s stopped, her teeth and gums look healthier, and she carries it around with or without the inserts. She loves it.
The con: the bristles come apart after aggressive chewing. She swallowed some and I caught the other side coming off.
So whenever I see this on sale, I buy several new ones. I don’t try to make it last and I check it often for damage.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 17, 2026
★★★★★ 5
Great Product
Size: Medium, Style: Jack
Great product. Kept our chewer busy for a long time
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 3, 2026
★★★★★ 3
Dog treat and chew bine
Size: Medium, Style: Bouncy Bone
This was an ok purchase for my little dog. After eating the treats. She definitely liked this treat. She is 2 years old and loves her treats. Disappointed, in that it does not last as long as they said it would.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 10, 2026
★★★★★ 5
Boxer Approved!
Size: Small, Style: Bristle Bone
One of my boxer girls (the fawn one in the video, 6 yrs old) hardly ever chews on things, my other boxer girl (the sealed brindle, 11 mos old) chews constantly and we're buying new nylabone chew toys 1-2 times a month for her. I wanted something to encourage my older girl to chew more for dental health and serotonin secretion, I know the benefits of chewing far outweigh the risks for dogs so I've been trying all kinds of things but hooves, ears and real bones get stinky and the girls stop caring for them after a few chew sessions, and my fawn baby only sometimes has interest in chew toys of any kind. When I found this with the different textures, materials (hard plastic, nylon bristles, rubber type discs, & jerky treat) I jumped for one, and it's a HUGE HIT!
She loves it, my 11 mo old loves it, and I definitely need backups because they're going to love this one to death in a couple weeks- I'm so happy about that!!
Between this and the new snuffle mat we bought at the same time, which both my girls go crazy for, I've finally found enrichment toys that boost my girls health both mentally and physically and they can BOTH get so much joy from them!!! Big wins for this dog momma, I'm ecstatic and grateful we've hit the spot for our babies!!
Would recommend and will buy again 10/10, seems durable after at least 5 chew sessions giving the girls turns of 10-15 min each, the video shows the wear from those sessions and it's not too rough yet. Their breath smells better after each session, and my older girl who hardly ever chews sometimes gets bloody gums when she does chew, that's gone away now that she's chewing this toy regularly for about 2 weeks, twice a week (working our way up slowly to 3-4 times weekly).
As you can see in the video, they don't even need the jerky treat anymore, they've fallen in love with the toy so much! But it helps encourage them to get their mouth working in different ways around the whole bone and not just one part, so I'll keep getting the treats for better overall coverage of the whole mouth getting cleaned. The size is a little small for my big boxer girls but not too small, they won't swallow any parts but they are mindful chewers, not too heavy-more like medium chewers, and they actually always choose the smaller toys over the big ones so it's perfect to pique their interest! Easy to take apart and clean, put in the treats and hand over to the dogs, they don't unscrew the end of the bone even if it gets a little loose during a chew sesh. We wash it with water after each use and set it out to dry, never gets stinky so far. Good value and great use for the money!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on June 20, 2024
★★★★★ 5
All 3 dogs, 3 different sizes and ages love it! Can’t go wrong!
Size: Medium, Style: Bristle Bone
Great! Super great! When you HAVE TO GET THEM OUT OF YOUR HAIR! This toy is durable even without the beef flavored insert! I have a Border Collie who has too much energy and an Aussie who can’t sit still and a small stray who is constantly figuring out a way to steal these from the other two! Safe, effective and actually cleans their teeth! This might well be my first Amazon review because this toy deserves it!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on March 19, 2026