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Description
ETD Recombinant Rabbit mAb (S-3661-43)Product Specification Host Rabbit Antigen ETD Synonyms Embryonic testis differentiation protein; Etd Immunogen Synthetic Peptide Accession Q80SW5 Clone Number S 3661 43 Antibody Type Recombinant mAb Isotype IgG Application IHC P Reactivity Ms Purification Protein A Concentration 0. 5 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS, 40% Glycerol, 0. 05% BSA, 0. 03% Proclin 300 Stability & Storage 12 months from date of
Product Specification
| Host | Rabbit |
| Antigen | ETD |
| Synonyms | Embryonic testis differentiation protein; Etd |
| Immunogen | Synthetic Peptide |
| Accession | Q80SW5 |
| Clone Number | S-3661-43 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | IHC-P |
| Reactivity | Ms |
| Purification | Protein A |
| Concentration | 0.5 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS, 40% Glycerol, 0.05% BSA, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt / reconstitution, -20 °C as supplied |
Dilution
| application | dilution | species |
| IHC-P | 1:2000 | Ms |
Background
Embryonic Testis Differentiation Protein (ETDP), often referred to in genomic databases as Embryonic Testis Differentiation protein homolog C (ETDC), is a protein-coding gene product primarily identified through homology in mammals (including humans and mice) that plays a specialized role during early male sexual development. Although its precise molecular mechanism remains an active area of research, ETDC is characterized by its specific expression in the embryonic testes, where it is hypothesized to contribute to the differentiation and maintenance of somatic cell lineages (such as Sertoli or Leydig cell precursors) or the regulation of germ cell quiescence following the sex-determination switch initiated by the Sry gene. As a homologous protein, it likely functions within the complex signaling network that ensures the proper morphogenesis of the testis cord and the suppression of female developmental pathways in XY embryos, making it a potential marker for studying disorders of sex development (DSD) and understanding the fine-tuned genetic control of gonadal differentiation before birth.
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