SKU: 90930449411

Spike S2(GCN4-IZ) His Tag Protein, SARS-CoV-2(K986P&V987P)

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Description

Spike S2(GCN4-IZ) His Tag Protein, SARS-CoV-2(K986P&V987P)Product Specification Species Human Synonyms Spike, S2 protein Accession P0DTC2 Amino Acid Sequence Ser686 Lys1211(K986P&V987P)

Product Specification


Species Human
Synonyms Spike, S2 protein
Accession P0DTC2
Amino Acid Sequence

Ser686-Lys1211(K986P&V987P) SVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTMYICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFGGFNFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFNGLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQNVLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGAISSVLNDILSRLDPPEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMSECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAHFPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELDSFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELGKYEQYIKGGGSGGGSGGGSRMKQIEDKIEEILSKIYHIENEIARIKKLVGERGGGSHHHHHH
Expression System HEK293
Molecular Weight 90-95kDa (Reducing)
Purity ＞95% by SDS-PAGE
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer PBS, pH7.4.
Reconstitution Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.
Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

1. Yuejun Shi, Jiale Shi, Limeng Sun, Yubei Tan, Gang Wang, Fenglin Guo, Guangli Hu, Yanan Fu, Zhen F Fu, Shaobo Xiao.Insight into vaccine development for Alpha-coronaviruses based on structural and immunological analyses of spike proteins. J Virol. 2021 Mar 10;95(7):e02284-20.Epub 2021 Jan 7.

Background

Coronaviruses that infect humans belong to the Alpha-coronavirus (including HCoV-229E) and Beta-coronavirus (including SARS-CoV and SARS-CoV-2) genera. In particular, SARS-CoV-2 is currently a major threat to public health worldwide. The spike (S) homotrimers bind to their receptors via the receptor-binding domain (RBD), which is a major target to block viral entry. our results reveal different vaccine strategies for coronaviruses, and S-trimer is better than RBD as a target for vaccine development in Alpha-coronavirus Our findings will provide important implications for future development of coronavirus vaccines. Outbreak of coronaviruses, especially SARS-CoV-2, poses a serious threat to global public health. Development of vaccines to prevent the coronaviruses that can infect humans has always been a top priority. Coronavirus spike (S) protein is considered as a major target for vaccine development. Currently, structural studies have shown that Alpha-coronavirus (HCoV-229E) and Beta-coronavirus (SARS-CoV and SARS-CoV-2) RBDs are in "lying" and "standing" states in the prefusion S-trimer structure. Here, we evaluated the ability of S-trimer and RBD to induce neutralizing antibodies among these coronaviruses. Our results showed that the S-trimer and RBD are both candidates for subunit vaccines in Beta-coronavirus (SARS-CoV and SARS-CoV-2) with a RBD "standing" state. However, for Alpha-coronavirus (HCoV-229E) with a RBD "lying" state, the S-trimer may be more suitable for subunit vaccines than the RBD. Our results will provide novel ideas for the development of vaccines targeting S protein in the future.

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SKU: 90930449411

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4.4 ★★★★★
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J
Jamie K.
Lake Worth, US
★★★★★ 5
Perfect for Adding Privacy to a Piano Studio
Size: 2 Panel 8FT W, Size: 2 Panel 8FT W
I Ordered the 2 Panel version which is way too big for my needs... that's on me. So keep in mind that the picture shows a fabric made for two panels only being used on one and hence it is not pulled tight; it would pull tight and not be so wrinkly if it was set up properly as two panels. The metal pools that make up the panels seem to be well made, stable, and of good quality. They were very easy to put together and they stand up tall with plenty of height. The appearance of it with the fabric on it isn't as elegant as it could be, but it still looks good enough. The material is plenty solid, not allowing light through it, and thereby making a solid barrier. I am using it to block the view out the studio door when a student is sitting at the piano to avoid distractions from the hallway. It will allow a student to enter the studio with our distracting the student who is at the piano.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 18, 2026
J
Just Me
Draper, US
★★★★★ 5
Room Divider That Gives Instant “This Is a Separate Space Now” Energy
Size: 3 Panel 12FT W
The Siebwin 3 Panel Folding Privacy Screen is surprisingly effective at changing the feel of a room without requiring construction, commitment, or somebody yelling about load bearing walls. The 12 foot width gives a substantial amount of coverage, making it useful for creating privacy, dividing open areas, blocking visual clutter, or setting up temporary sections within larger rooms. This saved us a ton of time and money in our new studio and enabled us to create a kitchen and office in one room. The wider feet make a huge difference because flimsy room dividers that collapse every time someone exhales too aggressively are deeply annoying. This one feels more stable and grounded once positioned. The folding design makes it easy to move around or adjust depending on the space, and it folds down relatively compactly when not in use. It is basically the introvert curtain wall of dreams. The material has a clean, neutral look that blends well into different room styles without screaming “temporary office cubicle panic.” It works well for apartments, studios, shared spaces, dressing areas, or simply hiding the mountain of chaos you swear you are going to organize tomorrow. Practical, portable, and refreshingly easy to use without turning setup into a three hour emotional event.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on May 16, 2026
S
Skeetre
Pawtucket, US
★★★★★ 4
It's 2 panels holding 1 big privacy screen. Can't use as 2 separate 4' panels, but works great.
Size: 2 Panel 8FT W
This 2 panel privacy screen works well. Assembly was very straight forward, with easily labeled tubes. My son and I had it together in about 10 minutes, which was probably 3 minutes of me telling him to quit playing around and hand me the parts. It feels very sturdy, not likely to fall over or anything. The material fits well, with the Velcro being very strong. Measurements are all very accurate, with all pieces attaching properly. We have a similar privacy screen at work that we have to try and stretch out because the top and bottom Velcro doesn't fit quite right... this model does not have any issues though. The material is thin and light weight, but solid black so that you can't see anything through or behind it. I definitely think it's a great deal for the money. What I think would have given it 5 stars though, is if you had 2 totally separate 4' panels instead of 2 panels with one big screen. It really wouldn't cost any extra to make it so that the screen was in 2 pieces and you could use it as 2 separate panels instead of having to use it as one big panel. It says 2 panel folding privacy screens, but it's really one big one that folds in the middle.
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Reviewed in the United States on May 25, 2026
C
Verified Purchase
creativecow
Charlottesville, US
★★★★★ 5
Game-Changer for My Space!
Color: White, Size: 4 Panel Basic
I recently purchased the Kecreque 4-Panel Room Divider, and it has completely transformed my living area. At 88" wide, it provides ample coverage, creating a private nook in my open-concept home. The white polyester fabric is not only sleek and modern but also wrinkle-resistant and easy to clean—just a quick wipe with a damp cloth, and it looks brand new. Assembly was a breeze; I had it set up in about 20 minutes. The metal frame feels sturdy and durable, and the three extra-wide metal feet offer excellent stability, ensuring it doesn't tip over easily. I love how the panels are connected with flexible buckles, allowing me to adjust the configuration to suit my needs—be it a straight line or an angled setup. This divider has been perfect for creating a dressing area in my bedroom, and I've also used it to section off a workspace in my living room. Its versatility is unmatched, and it folds down compactly when not in use, making storage hassle-free. If you're looking for a stylish, functional, and easy-to-use room divider, I highly recommend this one. It's been a fantastic addition to my home!
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Reviewed in the United States on June 7, 2025
M
Verified Purchase
Megan
Carnegie, US
★★★★★ 5
Sturdy and Functional
Color: White, Size: 4 Panel Basic
I got this to replace a poor quality divider that I tried first, and this thing is the best! It is easily folded, stands sturdily, easy to assemble, and the fabric looks great. Very very happy with the quality for the price.
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Reviewed in the United States on March 17, 2026

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