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Description
ICAM-1/CD54 His Tag Protein, MouseProduct Specification Species Mouse Synonyms BB2, ICAM1, CD54, P3. 58 Accession P13597 1 Amino Acid Sequence Gln28 Asn485, with C 8*His Expression System HEK293 Molecular Weight 72 95kDa Purity >95% by SDS PAGE Endotoxin <0. 1EU g Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, pH7. 4 Reconstitution Reconstitute at 0. 1 1 mg ml according to the size in ultrapure water after rapid centrifugation.
Product Specification
| Species | Mouse |
| Synonyms | BB2, ICAM1, CD54, P3.58 |
| Accession | P13597-1 |
| Amino Acid Sequence | Gln28-Asn485, with C-8*His |
| Expression System | HEK293 |
| Molecular Weight | 72-95kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <0.1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference |
1、Gu H F. et al. (2013) Association of intercellular adhesion molecule 1 (ICAM1) with diabetes and diabetic nephropathy. Front Endocrinol. 3: 179. 2、 Williams M R. et al. (2013) ICAM1 ligation‐induced transmigratory complex formation regulates leukocyte transendothelial migration. FASEB J. 27(S1): 57.5-57.5. |
Background
ICAM-1 is a cell surface glycoprotein expressed at a low basal level in immune, endothelial (EC) and epithelial cells, but is up-regulated in response to inflammatory stimulation. The function of ICAM-1 has been best studied in leukocyte transendothelial migration (TEM), where ICAM-1 regulates leukocyte rolling and adhesive interactions with the vessel wall, and guides leukocyte crossing of the endothelial layer. More recently, functional studies identified several new roles of ICAM-1 in epithelial injury-resolution responses, innate and adaptive immune responses in inflammation, and tumorigenesis.
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4.6 ★★★★★
Based on 6 reviews
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Product Reviews
★★★★★ 3
not durable.
Size: Large, Color: 5 Pack
My dog devoured these in 60 seconds - completely shredded
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 8, 2026
★★★★★ 5
No Mess, Lots of Fun!
Size: Large, Color: 5 Pack
My dog absolutely loves these toys! The squeakers and crinkle sounds keep him entertained for hours, and I appreciate that they have no stuffing—so no messy cleanup when he plays a little rough. The variety pack is great because it gives him different animals to choose from, and the toys are surprisingly durable even with lots of chewing.
They’re lightweight, easy for him to carry around, and perfect for playtime or keeping him busy when I’m working. Definitely a great value for the price, and I’ll be buying again when he wears them out. Highly recommend!
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Reviewed in the United States on August 21, 2025
★★★★★ 5
Great
Size: Large, Color: 5 Pack
These are big deal toys for our dogs. Use them when have to go out for a whole day. Have bought three sets over about two years. Takes them a several days to gut and get to the squeaker. They keep the skin around for months if we let them.
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Reviewed in the United States on March 10, 2026
★★★★★ 5
Dogs love them!
Size: Large, Color: 5 Pack
May dogs loved these. The squeaks last long enough but get lots of wear and tear. Worth money for the fun. My dog is 12 and still enjoys perfect size, weight, and flexibility.
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Reviewed in the United States on March 21, 2026
★★★★★ 5
GREAT Value even for a big boy.
Size: Large, Color: 5 Pack
My new 80lb husky/lab rescue LOVED his birthday present. They crinkle has he plays air-fetch w/himself! He does instantly puncture the squeekies at either end, but he's a large dog who chews. And these are SAFE for that. I figure 5 will last 2 months, but for the price? Who cares! He's worth it! Next time I'll go brighter colors because he tosses far &wide.
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Reviewed in the United States on April 22, 2026
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