Pay in installments of $70.00 with
,
and
Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Jul 15 - Jul 20
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
Biotinylated Siglec-4a His&Avi Tag Protein, HumanProduct Specification Species Human Synonyms MAG, Siglec 4a, GMA, S MAG Accession P20916 1 Amino Acid Sequence Gly20 Pro516, with C terminal 10*His&Avi tag
Product Specification
| Species | Human |
| Synonyms | MAG, Siglec-4a, GMA, S-MAG |
| Accession | P20916-1 |
| Amino Acid Sequence | Gly20-Pro516, with C-terminal 10*His&Avi tag GHWGAWMPSSISAFEGTCVSIPCRFDFPDELRPAVVHGVWYFNSPYPKNYPPVVFKSRTQVVHESFQGRSRLLGDLGLRNCTLLLSNVSPELGGKYYFRGDLGGYNQYTFSEHSVLDIVNTPNIVVPPEVVAGTEVEVSCMVPDNCPELRPELSWLGHEGLGEPAVLGRLREDEGTWVQVSLLHFVPTREANGHRLGCQASFPNTTLQFEGYASMDVKYPPVIVEMNSSVEAIEGSHVSLLCGADSNPPPLLTWMRDGTVLREAVAESLLLELEEVTPAEDGVYACLAENAYGQDNRTVGLSVMYAPWKPTVNGTMVAVEGETVSILCSTQSNPDPILTIFKEKQILSTVIYESELQLELPAVSPEDDGEYWCVAENQYGQRATAFNLSVEFAPVLLLESHCAAARDTVQCLCVVKSNPEPSVAFELPSRNVTVNESEREFVYSERSGLVLTSILTLRGQAQAPPRVICTARNLYGAKSLELPFQGAHRLMWAKIGPGGGSGGGSHHHHHHHHHHGLNDIFEAQKIEWHE |
| Expression System | HEK293 |
| Molecular Weight | 80-95kDa |
| Purity | >95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Conjugation | Biotin |
| Tag | Avi Tag, His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer | PBS, pH7.4 |
| Reconstitution | Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation. |
| Stability & Storage | · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃. · 3 months, -20 to -80℃ under sterile conditions after reconstitution. · 1 week, 2 to 8℃ under sterile conditions after reconstitution. · Please avoid repeated freeze-thaw cycles. |
| Reference | 1、Läubli H. et al. (2020) Sialic acid–binding immunoglobulin-like lectins (Siglecs) detect self-associated molecular patterns to regulate immune responses, Cellular and Molecular Life Sciences.77: 593-605. |
Background
Sialic acid-binding immunoglobulin-like lectins (Siglecs) are cell surface receptors of the I-type lectin family that are expressed on innate immune cells and bind to sialylated and non-sialylated ligands. Myelin-Associated Glycoprotein (MAG), also known as Siglec-4a, is a type I transmembrane glycoprotein belonging to the Siglec family, a subgroup of the Ig superfamily. It is selectively expressed by myelinating cells including Schwann cells in the peripheral nervous system (PNS) and oligodendrocytes in the central nervous system (CNS). It is encoded by a single gene that is conserved among vertebrates. It is composed of an extracellular segment containing five Ig-like domains, a single transmembrane segment, and a cytoplasmic domain. Mature MAG exists as two isoforms, termed S-MAG (short) and L-MAG (long), due to alternative splicing of the cytoplasmic domain.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy
4.8 ★★★★★
Based on 5 reviews
Sort
Product Reviews
★★★★★ 5
Nice material nice fit
Nice material nice fit
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on February 12, 2026
★★★★★ 5
Get it
Can't beat it for the price perfect to give casual wear a touch of class a lot better quality than I thought it would be very happy with the purchase
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on September 18, 2025
★★★★★ 5
Recommended
Size: Medium, Color: Black
Great fit and great quality. I do recommend this product.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 10, 2026
★★★★★ 5
Suprisingly good quality and a great looking jacket
I have been searching for a ring master jacket for a circus themed gala where I will be the Auctioneer/Ring Master. All the other jackets I looked at were either cheap costume stuff or just looked a little too much military Hussar style with all of the added gold tassels. This has just the right class and definitely the right look. I was worried it would fit weird or just not be constructed well but I could not be any happier with this jacket- the sleeves are a perfect length when my arms hang at my side, as is the high waist cut and the length of the tails are also just right- and best of all the sequins really shine.
I spent my career in the circus and the performing arts and this would have been more than acceptable on stage for someone to wear as a ring master or to look fancy and sparkly, assuming nobody will be standing on your shoulders and popping off your sequins. It is comfortable to wear, although I would not say it allows for full range of motion relative to a costume I would have actually worn in a circus while doing acrobatics. But that would be a totally hand made costume with flexible material and 4-10x the price.
Overall it cannot be beat for your average wearer!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 9, 2023
★★★★★ 5
Order big!
Flashy and fun. Runs small so order big!
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on January 21, 2026