SKU: 6360789387

FITC Human Anti-Human GM-CSF Antibody (S-2816)

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Description

FITC Human Anti-Human GM-CSF Antibody (S-2816)Product Specification Host Human Antigen GM CSF Synonyms Granulocyte macrophage colony stimulating factor; Colony stimulating factor (CSF); Molgramostin; Sargramostim; GMCSF; CSF2 Location Secreted Accession P04141 Clone Number S 2816 Antibody Type Recombinant mAb Application ICFCM Reactivity Hu Positive Sample Th1 Polarization Human PBMC Purification Protein A Concentration 0. 2 mg ml Conjugation FITC Physical Appearance Liquid Storage Buffer PBS, 1%

Product Specification


Host Human
Antigen GM-CSF
Synonyms Granulocyte-macrophage colony-stimulating factor; Colony-stimulating factor (CSF); Molgramostin; Sargramostim; GMCSF; CSF2
Location Secreted
Accession P04141
Clone Number S-2816
Antibody Type Recombinant mAb
Application ICFCM
Reactivity Hu
Positive Sample Th1 Polarization Human PBMC
Purification Protein A
Concentration 0.2 mg/ml
Conjugation FITC
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300

Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
ICFCM 5μl per million cells in 100μl volume Hu

Background

Granulocyte-macrophage colony-stimulating factor (GM-CSF), also known as CSF2, is a multifunctional glycoprotein cytokine that serves as a critical regulator of hematopoiesis and immune responses by binding to a specific heterodimeric receptor complex composed of an alpha chain (CD116) and a shared beta chain (CD131) on target cells. Primarily produced by activated macrophages, T cells, mast cells, endothelial cells, and fibroblasts in response to inflammatory stimuli, GM-CSF stimulates the proliferation, differentiation, survival, and functional activation of myeloid progenitor cells, driving their development into mature granulocytes (such as neutrophils, eosinophils, and basophils) and monocytes/macrophages while simultaneously enhancing the antimicrobial and antigen-presenting capabilities of these mature cells through mechanisms like increased phagocytosis, oxidative burst, and upregulation of MHC class II molecules. Beyond its physiological role in boosting host defense against infections and maintaining tissue homeostasis, GM-CSF plays a significant pathological role in chronic inflammatory and autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis, where its overproduction contributes to sustained inflammation and tissue damage, making it a prominent therapeutic target for monoclonal antibodies aimed at blocking its signaling pathway, while recombinant forms of the protein (e.g., sargramostim) are clinically utilized to accelerate myeloid recovery following chemotherapy or bone marrow transplantation.

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SKU: 6360789387

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Eva ZHANG
Waukegan, US
★★★★★ 5
Most importantly, its drainage system directs water into the tank, keeping it dry.
Color: Black, Size: Medium
This drain rack is small and fits perfectly on the edge of my sink. It's just the right size to hold hand soap and dishcloths, doesn't take up much space, and most importantly, it directs water directly into the sink, keeping it dry and keeping my sink clean and tidy.
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Reviewed in the United States on April 5, 2026
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Kathy Sweatmon
Los Angeles, US
★★★★★ 5
Good product
Color: Black, Size: Medium
It is as described, looks neat and tidy on the sink. Just big enough to do what I need it to do. My sink stays dry because the wate goes back int the sink.
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Reviewed in the United States on February 14, 2026
E
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Ethel White
Houston, US
★★★★★ 5
Quality is good.
Color: Black, Size: Medium
A product that works as promised.
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Reviewed in the United States on May 17, 2026
Y
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Yaelita
Pawtucket, US
★★★★★ 3
It is almost great.
Color: Black, Size: Medium
It is a nice sponge holder but the tray is not wide enough and it falls. Because it was the only one I found with a spout, I am keeping it, and figured a way to stick it so the tray doesn't fall. The other thing is that the tray is not sunken enough in the middle for all the water to be routed there, and the spout doesn't always get rid of all the water inside, so once in a few days, I have to manually press it down and more water comes out. The dishcloth rack is not great for cloths, they get wet. Other than that, it looks very nice, it is aesthetic, big enough for all my kitchen stuff, and makes my kitchen neater, so I like it.
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Reviewed in the United States on January 17, 2026
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Aprilfool
Houston, US
★★★★★ 4
Love this product very convenient
Color: Silver, Size: Medium
This was great to keep all my brushes, cloth, detergent and scrubby together and neat. I love the drainage and it looks clean. The only thing I don't care for is the bar that holds the cloth comes off all the time. Other than that it is great.
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Reviewed in the United States on March 30, 2026

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