SKU: 14685423751

FGF-6 Protein, Human

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Description

FGF-6 Protein, HumanProduct Specification Species Human Synonyms Fibroblast growth factor 6, FGF 6, Heparin secretory transforming protein 2 (HST 2; HSTF 2), Heparin binding growth factor 6 (HBGF 6) Accession P10767 Amino Acid Sequence Gly41 Ile208 Expression System E. coli Molecular Weight 14 15 kDa (Reducing) Purity >95% by SDS PAGE, >90% by HPLC. Endotoxin <0. 1EU g Conjugation Unconjugated Tag No Tag Physical Appearance Lyophilized powder Storage Buffer PBS, pH7. 4

Product Specification


Species Human
Synonyms Fibroblast growth factor 6, FGF-6, Heparin secretory-transforming protein 2 (HST-2; HSTF-2), Heparin-binding growth factor 6 (HBGF-6)
Accession P10767
Amino Acid Sequence

Gly41-Ile208

Expression System E.coli
Molecular Weight

14-15 kDa (Reducing)

Purity >95% by SDS-PAGE, >90% by HPLC.
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag No Tag
Physical Appearance Lyophilized powder
Storage Buffer

PBS, pH7.4

Reconstitution

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

Stability & Storage

·12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
·3 months, -20 to -80℃ under sterile conditions after reconstitution.
·1 week, 2 to 8℃ under sterile conditions after reconstitution.
·Please avoid repeated freeze-thaw cycles.

Reference

Genes & Dev. 1997;11(16):2040-2051.
Nat Commun. 2020;11(1):1421.

Background

Fibroblast growth factor 6 (FGF-6), also designated as HST2 or HBGF-6, is a secreted peptide growth factor belonging to the paracrine FGF subfamily. The FGF6 gene, located on human chromosome 12p13, encodes an 18.9 kDa protein that exhibits the highest expression in skeletal muscle and myogenic progenitor cells throughout embryonic development and adulthood. FGF-6 binds preferentially to fibroblast growth factor receptor 4 (FGFR4) with heparan sulfate proteoglycan co-receptor dependency, triggering downstream signaling through the MAPK/ERK1/2 and PI3K/AKT pathways.Functionally, FGF-6 operates as a dose-dependent regulator of myogenesis, promoting satellite cell proliferation at high concentrations and initiating myogenic differentiation via calcineurin-dependent pathways at lower concentrations. Beyond muscle physiology, FGF-6 exhibits pleiotropic functions in bone remodeling, iron homeostasis, thermogenesis, and oncogenesis, harboring both regenerative and tumorigenic activities.
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SKU: 14685423751

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Lowell, US
★★★★★ 4
A Great Value for the Time
Color: Rose Gold Black
Beautiful watch that looks far more expensive than it is. The rose gold finish is very attractive, and the black faux leather band goes well with it. It tells time accurately. The only caveat is the date window which is so tiny that it's very difficult to read when not under direct light. I am very pleased with my purchase.
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Fred Stoltzfus
Louisville, US
★★★★★ 5
Nice watch!
Color: black/black
This watch was very easy to set and keeps time very well. It looks great with a professional appearance it seems to be well built and the warranty is good. The glass on the first one I got cracked after two months and they are sending me a new one!
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Mindycochran
Natrona Heights, US
★★★★★ 5
Great value!
Color: black/black
Great value for the money. My teenage son started a watch collection, and this was the perfect addition. It looks like it cost a lot more than it really did.
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Reviewed in the United States on April 26, 2026
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Angela
Lexington, US
★★★★★ 5
Beautiful watch
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I bought this for my dad and he absolutely loves it. He says it keeps perfect time and tells me how much he loves it every time I see him.
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Reviewed in the United States on March 31, 2026
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Frank
Lowell, US
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Great watch
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I was impressed !
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Reviewed in the United States on April 5, 2026

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