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Description
Alexa Fluor 647-Labeled CD20 Flag&His Tag Full Length Protein, Human (Detergent)Product Specification Species Human Synonyms B lymphocyte surface antigen B1MS4A1B lymphocyte antigen CD20Membrane Spanning 4 Domains A1Leukocyte Surface Antigen Leu 16CD20 AntigenCD20Bp35Membrane Spanning 4 Domains Subfamily A Member 1CD20 ReceptorLEU 16CVID5MS4A2B1S7Antigens CD20Membrane Spanning 4 Domains Subfamily A Member 1B Lymphocyte Cell Surface Antigen B1 Accession P11836 Amino Acid Sequence Full length, with Flag tag at N Terminus, and His
Product Specification
| Species | Human |
| Synonyms | B-lymphocyte surface antigen B1，MS4A1，B-lymphocyte antigen CD20，Membrane Spanning 4-Domains A1，Leukocyte Surface Antigen Leu-16，CD20 Antigen，CD20，Bp35，Membrane-Spanning 4-Domains Subfamily A Member 1，CD20 Receptor，LEU-16，CVID5，MS4A2，B1，S7，Antigens， CD20，Membrane-Spanning 4-Domains， Subfamily A， Member 1，B-Lymphocyte Cell-Surface Antigen B1 |
| Accession | P11836 |
| Amino Acid Sequence | Full length, with Flag tag at N-Terminus, and His tag at C-Terminus |
| Expression System | HEK293 |
| Molecular Weight | 35.4 kDa |
| Conjugation | Alexa Fluor® 647 |
| Tag | His Tag, Flag Tag |
| Physical Appearance | Liquid |
| Storage Buffer | 25mM Hepes,150mM NaCl,0.02%DDM |
| Stability & Storage |
· 16 months from date of receipt stored at -80℃. |
| Reference | 1. Rougé L, Chiang N, Steffek M, et al. Structure of CD20 in complex with the therapeutic monoclonal antibody rituximab[J]. Science, 2020, 367(6483): 1224-1230. |
Background
CD20 is a 33-37 kDa non-glycosylated protein present on the surface of normal and malignant B lymphocytes and is a member of the MS4A (membrane-spanning 4-domain family A) protein family. The CD20 protein comprises four hydrophobic transmembrane domains, one intracellular domain, and two extracellular domains (a large loop and a small loop), with both the N- and C-termini located within the cytosol. CD20 is associated with several key molecules, including the major histocompatibility complex class II (MHCII), CD40 molecule, B-cell receptor (BCR), and the C-terminal src kinase-binding protein (CBP). CBP interacts with Src kinases such as LYN, FYN, and LCK.A deficiency in CD20 has been shown to result in a reduced number of circulating memory B cells, decreased isotype switching of immunoglobulins (Ig), and lower IgG antibody levels. It is also linked to various pathophysiological diseases and disorders.CD20 plays a crucial role in multiple physiological processes and is thus a promising therapeutic target. The CD20 protein product has the potential to enhance drug discovery efforts in related fields.
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4.5 ★★★★★
Based on 1759 reviews
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Product Reviews
★★★★★ 5
Actually Cooling Pillow
Size: Queen (1 Count), Color: Original White (Cooling)
This is a really nice pillow, I was worried it would be too soft or too firm but it's just right and it's actually cooling, it feels cool every time I touch it. I've noticed an improvement in sleep since using it. Would recommend!
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Reviewed in the United States on May 27, 2026
★★★★★ 5
Repurchased in King Size – Still Love These Cooling Pillows
Size: King (2 Count), Color: Original White (Cooling), Size: King (2 Count), Color: Original White (Cooling)
After using the queen-size version of these pillows for over a year, we purchased the king-size set when we upgraded to a king mattress. Both my husband and I really like them.
The cooling feature works well, and we like that each side feels different—when I run cold, I use the softer bamboo side, while my husband prefers the cooler side since he tends to sleep hot. They fit well in our king-size pillowcases and feel supportive in all sleeping positions, whether I’m on my stomach, side, or back.
I also appreciate that you can remove some of the filling to adjust the firmness. The covers are washable, which makes them easy to maintain. Overall, we’re very happy with this repurchase and the long-lasting comfort.
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Reviewed in the United States on April 15, 2026
★★★★★ 3
Not great at cooling
Size: Queen (2 Count), Color: Original White (Cooling)
Each pillow cover has 2 sides, one marked for cooling, and the other a different fabric. The cooling side is about the same effectiveness as having a silk or satin pillow cover. It's only cool when you first touch it. The cooling side doesn't seem to absorb or wick moisture, so if you are sweaty - it keeps the moisture in place. You'll definitely want a regular pillow case over the pillow cover. In fact, if you suffer from night sweats, the non-cooling side is actually more comfortable. The pillow fill is ample, and simple to squish around for more support for your neck, etc. Think bean bag. But it will retain your impression after use. I find I need to do as I did when I had down pillows - give it a few good shakes in the morning when I make the bed to get it evened out for the coming night. In all, it is a well-made and comfortable pillow to sleep on, but it does not excel in cooling.
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Reviewed in the United States on May 29, 2026
★★★★★ 5
excellent pillows i bought two sets!!
Size: Firm Queen (2 Count), Color: Original White (Cooling)
I ordered these for my son who has neck issues and has gone through so many pillows trying to find one that he liked. They’re heavy, so i was worried that they might be “too” heavy to be able to sleep on comfortably, so I ordered a second set, one firmer than the other (just in case) and gave him a set for Xmas and he loved the first set so much without even trying the less firm ones.He also needs the cooling factor and these offered that, too. They are filled with pieces of memory foam (tons of it) and each pillow can be modified by removing some of the foam. The covers are beautiful, high quality fabric with a zipper so ts easy to remove or replace the foam pieces. The size is perfect and they keep their shape. I kept the second set i ordered rather than returning them and i love the pillows. I actually modified two by removing some of the foam pieces. I kept the foam pieces in a zippered pillow protector and i can always adjust mine when or if i need to.
1000% love these.
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Reviewed in the United States on March 22, 2026
★★★★★ 5
The Perfect Firm Pillow l
Size: Queen (1 Count), Color: Original White (Cooling)
It is everything it claims to be, cool, comfortable and strong. I got this for my husband first, he loves it and then got one for my son, he uses it to support his knees and has been sleeping much better since then.
They both needed a firm pillow that is not super soft, firm but not achy.
Finally found the perfect one.
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Reviewed in the United States on May 6, 2026
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